Aquaporin 3 Antibody Properties Description Anti-Aquaporin 3 (RABBIT) Antibody - 600-401-E91 Host Rabbit Target Species Human Known Cross Reactivity Human, Mouse, Rat Clonality Polyclonal Application IF Microscopy : 1:200-400 Western Blot : 1:1000-4000 Physical State Liquid (sterile filtered) Shipping Condition Dry Ice Format IgG Label Unconjugated Concentration 1.0 mg/mL by UV absorbance at 280 nm Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 Preservative 0.1% (w/v) Sodium Azide Stabilizer 50% (v/v) Glycerol GeneName Aqp3 Relevant Links NCBI - NP_113891.1GeneID - 65133UniProtKB - P47862

Aquaporin 3 Antibody Description

Background Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins. Aquaporin 3 is found in the basolateral cell membrane ofprincipal collecting duct cells and provide a pathway for water to exit these cells. AQP3 gene expression is not regulated by vasopressin. Synonyms AQP3, Aquaporin 3 (GIL blood group), GIL, 31.4 kDa water channel protein, Aquaglyceroporin-3 Immunogen Aquaporin 3 Antibody was produced from whole rabbit serum prepared by repeated immunizations with a synthetic peptide correspronding to the C-terminal region. Immunogen Type Peptide Storage Condition Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. Application Note Anti-Aquaporin 3 Antibody is suitable for use in WB and IF microscopy. Expect a band approximately ~31.5kDa on specific lysates. May detect larger glycosylated bands ~35-50kDa. Specific conditions for reactivity should be optimized by the end user. Purity/Specifity Anti-Aquaporin 3 Antibody was purified by affinity chromatography. A BLAST analysis was used to suggest cross-reactivity with Aquaporin 3 from Human, Mouse, and Rat based on 100% homology with the immunizing sequence. Other species not yet tested. Cross-reactivity with Aquaporin 3 from other sources has not been determined. Channels and Transporters research. Disclaimer Note-General This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.