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主营:antibodies ,dpolyclonal
℡ 4000-520-616
℡ 4000-520-616
Rockland/Amyloid Oligomers (A11) Antibody/200-401-E88/100 µL
产品编号:200-401-E88
市  场 价:¥7180.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$359.00
品      牌: Rockland
公      司:Rockland Immunochemicals Inc.
公司分类:
Rockland/Amyloid Oligomers (A11) Antibody/200-401-E88/100 µL
商品介绍

AmyloidOligomers(A11)AntibodyProperties

Description
Anti-AmyloidOligomers(A11)(RABBIT)Antibody-200-401-E88
Host
Rabbit
TargetSpecies
Human
KnownCrossReactivity
Human,Mouse,Rat
Clonality
Polyclonal
Application
ELISA:0.1-10µg/mL
WesternBlot:1:1000
Immunohistochemistry:1:1000-10,000
ImmunoPrecipitation:1:1000
PhysicalState
Liquid(sterilefiltered)
ShippingCondition
DryIce
Format
IgG
Label
Unconjugated
Concentration
0.5mg/mLbyUVabsorbanceat280nm
Buffer
0.02MPotassiumPhosphate,0.15MSodiumChloride,pH7.2
Preservative
0.09%(w/v)SodiumAzide
StABIlizer
50%(v/v)Glycerol
GeneName
APP
RelevantLinks
NCBI-NM_000484.3

AmyloidOligomers(A11)AntibodyDescription

Background
Amyloidmonomericproteinscansometimesoligomerizeintodestructiveamyloidfibrils.Amyloidogenicconformationsofnon-diseaserelatedproteinscanbecreatedbypartialproteinmisfoldingordenaturation.Manydegenerativediseasesareknowntoberelatedtotheaccumulationofmisfoldedproteinsasamyloidfibres.Theseincludetheamyloid-ßpeptideplaquesandtauneurofibrillarytanglesinsenileplaquesofAlzheimer’ssymptomology,thedepositionofa-synucleinintheLewybodiesofParkinson’sdisease,andaccumulationofpolyglutamine-containingaggregatesinHuntington’sdisease.
Synonyms
AmyloidOligomeraß,A11,AmyloidbetaA4protein,ABPP,APPI,Alzheimerdiseaseamyloidprotein,Cerebralvascularamyloidpeptide,PreA4,Proteasenexin-II,APP,A4,AD1
Immunogen
AmyloidOligomers(A11)Antibodywasproducedfromwholerabbitserumpreparedbyrepeatedimmunizationswithsyntheticmolecularmimicofsolubleoligomers.
ImmunogenType
Peptide
StorageCondition
Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.
ApplicationNote
Anti-AmyloidFibrils(OC)AntibodyissuitableforuseinIP,IFmicroscopy,IHC,ELISA,WB,andDotblot.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.
Purity/Specifity
Anti-AmyloidOligomers(A11)AntibodywaspurifiedbyProteinAchromatography.ABLASTanalysiswasusedtosuggestcross-reactivitywithAmyloidOligomers(A11)fromEukaryotes,Human,Mouse,andRatbasedon100%homologywiththeimmunizingsequence.Recognizesalltypesofamyloidoligomers.Appearstorecognizeapeptidebackboneepitopethatiscommontoamyloidoligomers,butisnotfoundinnativeproteins,amyloidogenicmonomerormatureamyloidfibrils.Cross-reactivitywithAmyloidOligomers(A11)fromothersourceshasnotbeendetermined.Neuroscienceresearch.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
品牌介绍

ROCKLAND


Rockland Immunochemicals Inc. 成立于1962年,是一家全球性的生物技术公司,为功能基因组学,基因治疗和药物发现市场的基础,应用和临床研究制造领先的研究工具。


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