Rockland/Alpha Internexin Antibody/900-301-D04/100 µL,Rockland,,Rockland,rockland-inc,Rockland Immunochemicals Inc,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Rockland/Alpha Internexin Antibody/900-301-D04/100 µL

产品编号：900-301-D04

市场价：¥7100.00

场地：美国(厂家直采)

产品分类：抗体类>一抗>功能性抗体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$355.00

品牌： Rockland

公司：Rockland Immunochemicals Inc.

公司分类：

商品介绍

AlphaInternexinAntibodyProperties

Description

Anti-AlphaInternexin(Mouse)Antibody-900-301-D04

Host

Mouse

TargetSpecies

Rat

KnownCrossReactivity

human,mouse,rat

Clonality

MonoclonalID2

Application

ELISA:1:20,000
IFMicroscopy:1:250
WesternBlot:1:2000
Immunohistochemistry:1:1000

PhysicalState

Liquid

ShippingCondition

DryIce

Format

IgG

Label

Unconjugated

Buffer

0.02MPotassiumPhosphate,0.15MSodiumChloride,pH7.2

Preservative

0.01%(w/v)SodiumAzide

GeneName

INA

RelevantLinks

UniProtKB-P23565
GeneID-24503
UniProtKB-P23565.2

AlphaInternexinAntibodyDescription

Background

Anti-AlphaInternexinantibodyrecognizesalpha-internexinwhichisaClassIVintermediatefilamentoriginallydiscoveredasitco-purifieswithotherneurofilamentsubunits.Alpha-internexinisrelatedtobutdistinctfromthebetterknownneurofilamenttripletproteins,NF-L,NF-MandNF-H,havingsimilarproteinsequencemotifsandasimilarintronorganization.Itisexpressedonlyinneuronsandinlargeamountsearlyinneuronaldevelopment,butisdown-regulatedinmanyneuronsasdevelopmentproceeds.Manyclassesofmatureneuronscontainalpha-internexininadditiontoNF-L,NF-MandNF-H.Insomematureneuronsalpha-internexinistheonlyneurofilamentsubunitexpressed.Antibodiestoalpha-internexinarethereforeuniqueprobestostudyandclassifyneuronaltypesandfollowtheirprocessesinsectionsandintissueculture.Inaddition,recentstudiesshowamarkedup-regulationofalpha-internexinduringneuronalregeneration.Theuseofantibodiestothisproteininthestudyofbraintumorshasnotbeenexaminedtodate,butislikelytobeofinterest.RecentlyCairnsetal.usedthisantibodytoshowthatalpha-internexinisanabundantcomponentoftheinclusionsofneurofilamentinclusionbodydisease(NFID),aserioushumanneurodegenerativedisorder.Theantibodywasalsousedtoconfirmthepresenceofcirculatingauto-antibodiestoalpha-internexinintheseraofsomepatientswithendocrineautoimmunity,aswellasinsomenormalindividuals.Anti-AlphaInternexinantibodyisidealforinvestigatorsinvolvedinCellSignaling,Neuroscience,SignalTransductionresearch.

Synonyms

mouseanti-AlphaInternexinAntibody,AlphaINX,internexin,NF-66,NEF5

Immunogen

Anti-AlphaInternexinAntibodywasproducedbyrepeatedimmunizationswithrecombinantratalphainternexin.

ImmunogenType

RecombinantProtein

StorageCondition

Storevialat-20°Cpriortoopening. Thisproductisstableat4°Casanundilutedliquid. Forextendedstorage,aliquotcontentsandfreezeat-20°Corbelow. Avoidcyclesoffreezingandthawing.Diluteonlypriortoimmediateuse.

ApplicationNote

Anti-AlphaInternexinantibodyissuitableforuseinELISA,WesternBlotting,IHCandIF.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectabandofapproximately66kDainsizecorrespondingtoalphainternexinproteinsintheappropriatecelllysateorextract.

Purity/Specifity

Anti-AlphaInternexinAntibodyisdirectedagainstratAlphaInternexin.TheantibodyisatotalIgGfractionfromconcentratedclarifiedcellculturesupernate.Anti-AlphaInternexinantibodycanbeusedonformalin-fixedcellsintissueculture,cryostatsections,andWesternblotting.TheepitoperecognizedbytheID2cloneisintheC-terminalnon-helicalextensionoftheproteinandisunusuallyresistanttoaldehydefixation,sothatthisantibodyisidealforstudiesofparaffinembeddedformalinfixedhistologicalsections.Reactivityisexpectedagainsthumanandmouse.Crossreactivityfromothersourceshasnotbeendetermined.

DisclaimerNote-General

Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitABIlityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.

品牌介绍

ROCKLAND

Rockland Immunochemicals Inc. 成立于1962年，是一家全球性的生物技术公司，为功能基因组学，基因治疗和药物发现市场的基础，应用和临床研究制造领先的研究工具。

产品列表：

No.	品牌	货号	名称	规格
1	ROCKLAND	100-4191	Superoxide Dismutase Antibody	2mL
2	ROCKLAND	100-4140	Acid Phosphatase Antibody	2ml
3	ROCKLAND	200-301-U98	5-mC Antibody	50ug
4	ROCKLAND	200-301-065s	NF-kB p65 Antibody	25ul
5	ROCKLAND	200-301-065	NF-kB p65 Antibody	100ug
6	ROCKLAND	200-303-400	ATM phospho S1981 Peroxidase Conjugated Antibody	100ug
7	ROCKLAND	600-401-952	IRAK-2 Antibody	100ug
8	ROCKLAND	609-1606	Human IgA (alpha chain) Antibody Biotin Conjugated	1mg
9	ROCKLAND	600-401-147	Alpha-1-Trypsin Antibody	1mg
10	ROCKLAND	610-4610	Mouse κ (kappa chain) Antibody Biotin Conjugated	1mg
11	ROCKLAND	609-1316	Human IgG (H&L) Antibody Peroxidase Conjugated Pre-Adsorbed	2mg
12	ROCKLAND	613-4528	Sheep IgG (H&L) Secondary Antibody Alkaline Phosphatase Conjugated Pre-Adsorbed	500ug
13	ROCKLAND	805-7602	Fab Goat IgG Antibody Biotin Conjugated	1mg
14	ROCKLAND	714-406-002	F(ab')2 Swine IgG (H&L) Antibody Biotin Conjugated	500ug
15	ROCKLAND	600-401-147S	Alpha-1-Trypsin Antibody	25ul