Rockland/ABCA4 Rim Protein Antibody/200-301-D05/100 µL,Rockland,,Rockland,rockland-inc,Rockland Immunochemicals Inc,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Rockland/ABCA4 Rim Protein Antibody/200-301-D05/100 µL

产品编号：200-301-D05

市场价：¥7100.00

场地：美国(厂家直采)

产品分类：抗体类>一抗>功能性抗体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$355.00

品牌： Rockland

公司：Rockland Immunochemicals Inc.

公司分类：

商品介绍

ABCA4RimProteinAntibodyProperties

Description

Anti-ABCA4(RimProtein)(Mouse)MonoclonalAntibody-200-301-D05

Host

Mouse

TargetSpecies

Bovine

KnownCrossReactivity

bovine,human,mouse,Xenopus

Clonality

Monoclonal3F4IgG

Application

ELISA:1:10,000
WesternBlot:1:1000
Immunohistochemistry:1:100

PhysicalState

Liquid

ShippingCondition

DryIce

Format

IgG

Label

Unconjugated

Buffer

0.01MHEPES,0.15MSodiumChloride,pH7.5

StABIlizer

0.1mg/mlBovineSerumAlbumin(BSA)-IgGandProteasefree,50%(v/v)Glycerol

GeneName

ABCA4

RelevantLinks

UniProtKB-O35600
GeneID-11304
NCBI-NP_776646.1

ABCA4RimProteinAntibodyDescription

Background

ABCA4antibodydetectsABCA4(ATP-bindingcassette,sub-familyA(ABC1),member4,RimProtein)amemberofthesuperfamilyofATP-bindingcassette(ABC)transporters.ABCproteinstransportvariousmoleculesacrossextra-andintracellularmembranes.ABCA4isaretina-specificABCtransporterwithN-retinylidene-PEasasubstrate.Itisexpressedexclusivelyinretinaphotoreceptorcells,indicatingthegeneproductmediatestransportofanessentialmoleculeacrossthephotoreceptorcellmembrane.MutationsinthisgenearefoundinpatientsdiagnosedwithStargardtdiseaseandareassociatedwithretinitispigmentosa-19andage-relatedmaculardegeneration.DefectsinABCA4arethecauseofStargardtdiseasetype1(STGD1).STGDisoneofthemostfrequentcausesofmaculardegenerationinchildhood.DefectsinABCA4arealsoknowntocausefundusflavimaculatus(FFM),age-relatedmaculardegenerationtype2(ARMD2)andcone-roddystrophytype3(CORD3).Anti-ABCA4antibodyisidealforinvestigatorsinvolvedinCellSignaling,Neuroscience,SignalTransductionresearch.

Synonyms

Retinal-specificATP-bindingcassettetransporter,ATP-bindingcassettesub-familyAmember4,RIMABCtransporter

Immunogen

Anti-ABCA4antibodywasproducedbyrepeatedimmunizationswithpartiallypurifiedbovine220-kDadiscrimprotein.

ImmunogenType

NativeProtein

StorageCondition

Storevialat-20°Cpriortoopening. Thisproductisstableat4°Casanundilutedliquid. Forextendedstorage,aliquotcontentsandfreezeat-20°Corbelow. Avoidcyclesoffreezingandthawing.Diluteonlypriortoimmediateuse.

ApplicationNote

Anti-ABCA4antibodyissuitableforuseinELISA,WesternBlottingandIHC.Specificconditionsshouldbeoptimizedbytheenduser.Expectabandof~250kDainsizecorrespondingtoABCA4proteinsintheappropriatecelllysateorextract.

Purity/Specifity

Anti-ABCA4antibodyisdirectedagainstbovineABCA4RimProtein.TheantibodywasProteinGpurifiedfromculturesupernatant.Reactivityisexpectedagainsthuman,mouseandXenopus.Cross-reactivitywithABCA4fromothersourceshasnotbeendetermined.

DisclaimerNote-General

Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.

品牌介绍

ROCKLAND

Rockland Immunochemicals Inc. 成立于1962年，是一家全球性的生物技术公司，为功能基因组学，基因治疗和药物发现市场的基础，应用和临床研究制造领先的研究工具。

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