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主营:antibodies ,dpolyclonal
℡ 4000-520-616
℡ 4000-520-616
Rockland/Aquaporin 4 Antibody/600-401-E92/100 µL
产品编号:600-401-E92
市  场 价:¥7180.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$359.00
品      牌: Rockland
公      司:Rockland Immunochemicals Inc.
公司分类:
Rockland/Aquaporin 4 Antibody/600-401-E92/100 µL
商品介绍

Aquaporin4AntibodyProperties

Description
Anti-Aquaporin4(RABBIT)Antibody-600-401-E92
Host
Rabbit
TargetSpecies
Human
KnownCrossReactivity
Human,Mouse,Rat
Clonality
Polyclonal
Application
IFMicroscopy:1:400
WesternBlot:1:1000-4000
PhysicalState
Liquid(sterilefiltered)
ShippingCondition
DryIce
Format
IgG
Label
Unconjugated
Concentration
1mg/mLbyUVabsorbanceat280nm
Buffer
0.02MPotassiumPhosphate,0.15MSodiumChloride,pH7.2
Preservative
0.1%(w/v)SodiumAzide
StABIlizer
50%(v/v)Glycerol
GeneName
Aqp4
RelevantLinks
NCBI-NP_036957.1
GeneID-25293
UniProtKB-P47863

Aquaporin4AntibodyDescription

Background
Aquaporinsselectivelyconductwatermoleculesinandoutofthecell,whilepreventingthepassageofionsandothersolutes.Knownaswaterchannels,theyareintegralmembraneporeproteins.Aquaporin4isconstitutivelyexpressedinthebasolateralcellmembraneofprincinpalcollectingductcellsinthekidneyandprovideapathwayforwatertoexitthesecells.ItisalsoexpressedinastrocytesandisupregulatedbydirectinsulttotheCNS.Aquaporin4hasbeenpropsedastheprimaryautoimmunetargetinneuromyelitisoptica.
Synonyms
AQP4,Aquaporin-4,Mercurial-insensitivewaterchannel,MIWC,WCH4
Immunogen
Aquaporin4AntibodywasproducedfromwholerabbitserumpreparedbyrepeatedimmunizationswithasyntheticpeptidecorresprondingtotheC-terminalregion.
ImmunogenType
Peptide
StorageCondition
Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.
ApplicationNote
Anti-Aquaporin4AntibodyissuitableforuseinWBandIFmicroscopy.Expectabandapproximately~35kDaonspecificlysates.Maydetectlargerglycosylatedbands~50kDa.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.
Purity/Specifity
Anti-Aquaporin4Antibodywaspurifiedbyaffinitychromatography.ABLASTanalysiswasusedtosuggestcross-reactivitywithAquaporin4fromHuman,Mouse,andRatbasedon100%homologywiththeimmunizingsequence.Otherspeciesnotyettested.Cross-reactivitywithAquaporin4fromothersourceshasnotbeendetermined.ChannelsandTransportersresearch.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
品牌介绍

ROCKLAND


Rockland Immunochemicals Inc. 成立于1962年,是一家全球性的生物技术公司,为功能基因组学,基因治疗和药物发现市场的基础,应用和临床研究制造领先的研究工具。


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