Rockland/Aquaporin 2 phospho S261 Antibody/612-401-D08/100 µL,Rockland,,Rockland,rockland-inc,Rockland Immunochemicals Inc,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Rockland/Aquaporin 2 phospho S261 Antibody/612-401-D08/100 µL

产品编号：612-401-D08

市场价：¥7100.00

场地：美国(厂家直采)

产品分类：抗体类>一抗>功能性抗体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$355.00

品牌： Rockland

公司：Rockland Immunochemicals Inc.

公司分类：

商品介绍

Aquaporin2phosphoS261AntibodyProperties

Description

Anti-Aquaporin2pS261(Rabbit)Antibody-612-401-D08

Host

Rabbit

TargetSpecies

Rat

KnownCrossReactivity

rat

Clonality

Polyclonal

Application

ELISA:1:10,000
WesternBlot:1:1000

PhysicalState

Liquid

ShippingCondition

DryIce

Format

IgG

Label

Unconjugated

Buffer

0.01MHEPES,0.15MSodiumChloride,pH7.5

StABIlizer

0.1mg/mlBovineSerumAlbumin(BSA)-IgGandProteasefree,50%(v/v)Glycerol

GeneName

AQP2

RelevantLinks

UniProtKB-P34080
GeneID-25386
UniProtKB-P34080.1

Aquaporin2phosphoS261AntibodyDescription

Background

Aquaporin2pS261antibodyrecognizesaquaporin2(AQP2)whichisahormonallyregulatedwaterchannellocatedintherenalcollectingduct.MutationsintheAQP2genecausehereditarynephrogenicdiabetesinsipidusinhumans.AvasopressininducedcAMPincreaseresultsinthephosphorylationofAQP2atserine-256anditstranslocationfromtheintracellularvesiclestotheapicalmembraneofprincipalcells.Recently,serine-261hasbeenidentifiedasanovelphosphorylationsiteonAQP2andlevelsofphosphorylatedS261havebeenshowntodecreasewithvasopressintreatmentsuggestingitsinvolvementinvasopressin-dependentAQP2trafficking.Anti-Aquaporin2pS261antibodyisidealforinvestigatorsinvolvedinCellSignaling,Neuroscience,SignalTransductionresearch.

Synonyms

ADHwaterchannel,Aquaporin-CD,Collectingductwaterchannelprotein,WCH-CD,Waterchannelproteinforrenalcollectingduct

Immunogen

Anti-Aquaporin2pS261Antibodywasproducedbyrepeatedimmunizationswithsyntheticphospho-peptidecorrespondingtoaminoacidresiduessurroundingSer261.

ImmunogenType

Peptide

PostTranslationalModification

Phosphorylation

StorageCondition

Storevialat-20°Cpriortoopening. Thisproductisstableat4°Casanundilutedliquid. Forextendedstorage,aliquotcontentsandfreezeat-20°Corbelow. Avoidcyclesoffreezingandthawing.Diluteonlypriortoimmediateuse.

ApplicationNote

Anti-Aquaporin2pS261antibodyissuitableforuseinELISA,WesternBlotting.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectabandofapproximately29kDaAQP2proteinphosphorylatedatSer261intheappropriatecelllysateorextract.Thisantibodyalsorecognizestheglycosylatedforofaquaporin2atapproximately37kDainsize.

Purity/Specifity

Anti-Aquaporin2pS261AntibodyisdirectedagainstratAquaporin2proteinphosphorylatedatS261.Theantibodywaspreparedfrommonospecificantiserumbyimmunoaffinitychromatographyusingphosphopeptidecoupledtoagarosebeadsfollowedbysolidphaseadsorption(s)againstnon-phosphopeptideandnon-specificpeptidetoremoveanyunwantedreactivities.Assaybyimmunoelectrophoresisresultedinasingleprecipitinarcagainstanti-RabbitSerum.Minimalreactivityoccursagainstnon-phosphorylatedAquaporin2.ReactivityagainstAquaporin2occursfromratsources.However,reactivityisalsoexpectedagainstthefollowingspeciesbasedon100%sequencehomology:canineandbovine,chicken,human,mouseandnon-humanprimate.

DisclaimerNote-General

Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.

品牌介绍

ROCKLAND

Rockland Immunochemicals Inc. 成立于1962年，是一家全球性的生物技术公司，为功能基因组学，基因治疗和药物发现市场的基础，应用和临床研究制造领先的研究工具。

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