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主营:antibodies ,dpolyclonal
℡ 4000-520-616
℡ 4000-520-616
Rockland/APP Antibody/600-401-G76/100 µg
产品编号:600-401-G76
市  场 价:¥7180.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$359.00
品      牌: Rockland
公      司:Rockland Immunochemicals Inc.
公司分类:
Rockland/APP Antibody/600-401-G76/100 µg
商品介绍

APPAntibodyProperties

Description
Anti-APP(RABBIT)Antibody-600-401-G76
Host
Rabbit
TargetSpecies
Human
KnownCrossReactivity
Human,Mouse,Rat
Clonality
Polyclonal
Application
WesternBlot:0.5-1ug/mL
PhysicalState
Liquid(sterilefiltered)
ShippingCondition
DryIce
Format
IgG
Label
Unconjugated
Concentration
1mg/mLbyUVabsorbanceat280nm
Buffer
0.02MPotassiumPhosphate,0.15MSodiumChloride,pH7.2
Preservative
0.01%(w/v)SodiumAzide
GeneName
AmyloidbetaA4protein
RelevantLinks
NCBI-CAA30050
UniProtKB-P05067
GeneID-351

APPAntibodyDescription

Background
APPantibodydetectsthehumanamyloidA4protein.Accumulationoftheamyloid-betapeptide(Abeta)inthecerebralcortexisacriticaleventinthepathogenesisofAlzheimer"sdisease.Thebeta-amyloidproteinprecursor(APP)iscleavedbybeta-secretase,producingasolublederivativeoftheproteinandamembraneanchored99-aminoacidcarboxy-terminalfragment(C99).TheC99fragmentservesassubstrateforgamma-secretasetogeneratethe4kDaamyloid-betapeptide(Abeta),whichisdepositedinthebrainsofallsuffersofAlzheimer"sdisease.Anti-APPisidealforinvestigatorsthatareinvolvedinNeuroscienceresearch.
Synonyms
APP(AbNT),APP(AbNT),ABPP
Immunogen
APPAntibodywasproducedfromwholerabbitserumpreparedbyrepeatedimmunizationswithapeptidecorrespondingtoaminoacidsofhumanamyloidA4proteinprecursor(APP)correspondingtothen-terminusofthe4KAbpeptidegeneratedbyb-andg-secretases.Thepeptidesequencesareidenticaltothoseofrabbit,pig,bovine,guineapig,andchicken.
ImmunogenType
Peptide
StorageCondition
Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.
ApplicationNote
Anti-APPAntibodyissuitableforuseinE,WB,andIHC.Expectabandapproximately~86.9kDaonspecificlysates.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.
Purity/Specifity
Anti-APPAntibodywasaffinitypurifiedfrommonospecificantiserumbyimmunoaffinitypurification.ABLASTanalysiswasusedtosuggestcross-reactivitywithAPPwithHuman,MouseandRatbasedon100%homologywiththeimmunizingsequence.Cross-reactivitywithAPPfromothersourceshasnotbeendetermined.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitABIlityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
品牌介绍

ROCKLAND


Rockland Immunochemicals Inc. 成立于1962年,是一家全球性的生物技术公司,为功能基因组学,基因治疗和药物发现市场的基础,应用和临床研究制造领先的研究工具。


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