Rockland/APOLIPOPROTEIN A-I Antibody/600-101-109/1 mg,Rockland,,Rockland,rockland-inc,Rockland Immunochemicals Inc,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Rockland/APOLIPOPROTEIN A-I Antibody/600-101-109/1 mg

产品编号：600-101-109

市场价：¥20380.00

场地：美国(厂家直采)

产品分类：抗体类>一抗>功能性抗体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$1019.00

品牌： Rockland

公司：Rockland Immunochemicals Inc.

公司分类：

商品介绍

APOLIPOPROTEINA-IAntibodyProperties

Description

Anti-ApolipoproteinA-I(GOAT)Antibody-600-101-109

Host

Goat

TargetSpecies

Human

KnownCrossReactivity

human

Clonality

Polyclonal

Application

ELISA:1:10,000-1:20,000
WesternBlot:1:1,000-1:2,000
Immunohistochemistry:1:50-1:200
ImmunoPrecipitation:1:100
OtherDilution:UserOptimized

PhysicalState

Liquid(sterilefiltered)

ShippingCondition

WetIce

Format

IgG

Label

Unconjugated

Concentration

1.0mg/mLbyUVabsorbanceat280nm

Buffer

0.125MSodiumBorate,0.075MSodiumChloride,0.005MEDTA,pH8.0

Preservative

0.01%(w/v)SodiumAzide

StABIlizer

None

GeneName

APOA1

RelevantLinks

UniProtKB-P02647
NCBI-4557321
GeneID-335

APOLIPOPROTEINA-IAntibodyDescription

Background

AntiApolipoproteinA-IantibodyrecognizesthegeneproductofAPOA1.Apolipoproteinpromotescholesteroleffluxfromtissuestotheliverforexcretion.ApolipoproteinA-Iisthemajorproteincomponentofhighdensitylipoprotein(HDL)intheplasma.Synthesizedintheliverandsmallintestine,itconsistsoftwoidenticalchainsof77aminoacids;an18-aminoacidsignalpeptideisremovedco-translationallyanda6-aminoacidpropeptideiscleavedpost-translationally.Variationinthelatterstep,inadditiontomodificationsleADIngtoso-calledisoforms,isresponsIBLeforsomeofthepolymorphismobserved.APOA1isacofactorforlecithincholesterolacyltransferase(LCAT)whichisresponsiblefortheformationofmostplasmacholesterylesters.TheAPOA1,APOC3andAPOA4genesarecloselylinkedinbothratandhumangenomes.TheA-IandA-IVgenesaretranscribedfromthesamestrand,whiletheC-IIIgeneistranscribedconvergentlyinrelationtoA-I.DefectsintheapolipoproteinA-1geneareassociatedwithHDLdeficiencyandTangierdisease.Thisantibodyissuitableforcardiovascularresearch.

Synonyms

goatanti-ApolipoproteinA-IAntibody,goatanti-APOA1antibody,goatanti-APO-A1antibody,goatanti-APOA-1antibody,APOA1/APOC3fusiongeneantibody,ApolipoproteinAIprecursorantibody,ApolipoproteinAIantibody,Apolipoproteinofhighdensitylipoproteinantibody,ProapoA-I,ProapolipoproteinA-I

Immunogen

apoLipoproteinTypeA-IwasisolatedfromhumanplasmabydensitygradientcentrifugationfollowedbyHPLCpurification.

ImmunogenType

NativeProtein

StorageCondition

Storevialat4°Cpriortoopening. Thisproductisstableat4°Casanundilutedliquid. Diluteonlypriortoimmediateuse. Forextendedstoragemixwithanequalvolumeofglycerol,aliquotcontentsandfreezeat-20°Corbelow. Avoidcyclesoffreezingandthawing.

ApplicationNote

Anti-apoLipoproteinantibodieshavebeenusedforindirecttrappingELISAforquantitationofantigeninserumusingastandardcurve,forimmunoprecipitation,immunohistochemistryandforwesternblottingforhighlysensitivequalitativeanalysis.

Purity/Specifity

Thisproducthasbeenpreparedbyimmunoaffinitychromatographyusingimmobilizedantigensfollowedbyextensivecross-adsorptionagainstotherapoLipoproteinsandhumanserumproteinstoremoveanyunwantedspecificities. Typicallylessthan1%cross-reactivityagainstothertypesofapoLipoproteinwasdetectedbyELISAagainstpurifiedstandards. ThisantibodyreactswithhumanapoLipoproteinA-Iandhasnegligiblecross-reactivitywithTypeA-II,B,C-I,C-II,C-III,EandJapoLipoproteins. Specificcross-reactionofanti-apoLipoproteinantibodieswithantigensfromotherspecieshasnotbeendetermined. Non-specificcross-reactionofanti-apoLipoproteinantibodieswithotherhumanserumproteinsisnegligible.

DisclaimerNote-General

Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.

品牌介绍

ROCKLAND

Rockland Immunochemicals Inc. 成立于1962年，是一家全球性的生物技术公司，为功能基因组学，基因治疗和药物发现市场的基础，应用和临床研究制造领先的研究工具。

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