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主营:antibodies ,dpolyclonal
℡ 4000-520-616
℡ 4000-520-616
Rockland/APOLIPOPROTEIN A-I Antibody/600-101-109/1 mg
产品编号:600-101-109
市  场 价:¥20380.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$1019.00
品      牌: Rockland
公      司:Rockland Immunochemicals Inc.
公司分类:
Rockland/APOLIPOPROTEIN A-I Antibody/600-101-109/1 mg
商品介绍

APOLIPOPROTEINA-IAntibodyProperties

Description
Anti-ApolipoproteinA-I(GOAT)Antibody-600-101-109
Host
Goat
TargetSpecies
Human
KnownCrossReactivity
human
Clonality
Polyclonal
Application
ELISA:1:10,000-1:20,000
WesternBlot:1:1,000-1:2,000
Immunohistochemistry:1:50-1:200
ImmunoPrecipitation:1:100
OtherDilution:UserOptimized
PhysicalState
Liquid(sterilefiltered)
ShippingCondition
WetIce
Format
IgG
Label
Unconjugated
Concentration
1.0mg/mLbyUVabsorbanceat280nm
Buffer
0.125MSodiumBorate,0.075MSodiumChloride,0.005MEDTA,pH8.0
Preservative
0.01%(w/v)SodiumAzide
StABIlizer
None
GeneName
APOA1
RelevantLinks
UniProtKB-P02647
NCBI-4557321
GeneID-335

APOLIPOPROTEINA-IAntibodyDescription

Background
AntiApolipoproteinA-IantibodyrecognizesthegeneproductofAPOA1.Apolipoproteinpromotescholesteroleffluxfromtissuestotheliverforexcretion.ApolipoproteinA-Iisthemajorproteincomponentofhighdensitylipoprotein(HDL)intheplasma.Synthesizedintheliverandsmallintestine,itconsistsoftwoidenticalchainsof77aminoacids;an18-aminoacidsignalpeptideisremovedco-translationallyanda6-aminoacidpropeptideiscleavedpost-translationally.Variationinthelatterstep,inadditiontomodificationsleADIngtoso-calledisoforms,isresponsIBLeforsomeofthepolymorphismobserved.APOA1isacofactorforlecithincholesterolacyltransferase(LCAT)whichisresponsiblefortheformationofmostplasmacholesterylesters.TheAPOA1,APOC3andAPOA4genesarecloselylinkedinbothratandhumangenomes.TheA-IandA-IVgenesaretranscribedfromthesamestrand,whiletheC-IIIgeneistranscribedconvergentlyinrelationtoA-I.DefectsintheapolipoproteinA-1geneareassociatedwithHDLdeficiencyandTangierdisease.Thisantibodyissuitableforcardiovascularresearch.
Synonyms
goatanti-ApolipoproteinA-IAntibody,goatanti-APOA1antibody,goatanti-APO-A1antibody,goatanti-APOA-1antibody,APOA1/APOC3fusiongeneantibody,ApolipoproteinAIprecursorantibody,ApolipoproteinAIantibody,Apolipoproteinofhighdensitylipoproteinantibody,ProapoA-I,ProapolipoproteinA-I
Immunogen
apoLipoproteinTypeA-IwasisolatedfromhumanplasmabydensitygradientcentrifugationfollowedbyHPLCpurification.
ImmunogenType
NativeProtein
StorageCondition
Storevialat4°Cpriortoopening.  Thisproductisstableat4°Casanundilutedliquid. Diluteonlypriortoimmediateuse. Forextendedstoragemixwithanequalvolumeofglycerol,aliquotcontentsandfreezeat-20°Corbelow. Avoidcyclesoffreezingandthawing.
ApplicationNote
Anti-apoLipoproteinantibodieshavebeenusedforindirecttrappingELISAforquantitationofantigeninserumusingastandardcurve,forimmunoprecipitation,immunohistochemistryandforwesternblottingforhighlysensitivequalitativeanalysis.
Purity/Specifity
Thisproducthasbeenpreparedbyimmunoaffinitychromatographyusingimmobilizedantigensfollowedbyextensivecross-adsorptionagainstotherapoLipoproteinsandhumanserumproteinstoremoveanyunwantedspecificities. Typicallylessthan1%cross-reactivityagainstothertypesofapoLipoproteinwasdetectedbyELISAagainstpurifiedstandards. ThisantibodyreactswithhumanapoLipoproteinA-Iandhasnegligiblecross-reactivitywithTypeA-II,B,C-I,C-II,C-III,EandJapoLipoproteins. Specificcross-reactionofanti-apoLipoproteinantibodieswithantigensfromotherspecieshasnotbeendetermined. Non-specificcross-reactionofanti-apoLipoproteinantibodieswithotherhumanserumproteinsisnegligible.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
品牌介绍

ROCKLAND


Rockland Immunochemicals Inc. 成立于1962年,是一家全球性的生物技术公司,为功能基因组学,基因治疗和药物发现市场的基础,应用和临床研究制造领先的研究工具。


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