Rockland/Apc11 Antibody/100-401-A15/100 µL,Rockland,,Rockland,rockland-inc,Rockland Immunochemicals Inc,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Rockland/Apc11 Antibody/100-401-A15/100 µL

产品编号：100-401-A15

市场价：¥7180.00

场地：美国(厂家直采)

产品分类：抗体类>一抗>功能性抗体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$359.00

品牌： Rockland

公司：Rockland Immunochemicals Inc.

公司分类：

商品介绍

Apc11AntibodyProperties

Description

Anti-APC11(C-terminalspecific)(RABBIT)Antibody-100-401-A15

Host

Rabbit

TargetSpecies

Human

KnownCrossReactivity

human

Clonality

Polyclonal

Application

ELISA:1:2,000-1:10,000
WesternBlot:1:500-1:1,000
Immunohistochemistry:UserOptimized
OtherDilution:UserOptimized

PhysicalState

Liquid(sterilefiltered)

ShippingCondition

DryIce

Format

Antiserum

Label

Unconjugated

Concentration

85mg/mLbyRefractometry

Buffer

None

Preservative

0.01%(w/v)SodiumAzide

StABIlizer

None

GeneName

ANAPC11

RelevantLinks

UniProtKB-Q9NYG5
NCBI-19924286
GeneID-51529

Apc11AntibodyDescription

Background

APC11isalsoknownasAnaphasepromotingcomplexsubunit11,APC11,Cyclosomesubunit11,HepatocellularcarcinomaassociatedRINGfingerprotein,andHSPC214. APC11isacomponentoftheanaphasepromotingcomplex/cyclosome(APC/C),acellcycle-regulatedE3ubiquitinligasethatcontrolsprogressionthroughmitosisandtheG₁phaseofthecellcycle.APC11mayfunctiontorecruittheE2ubiquitin-conjugatingenzymestothecomplex. APC11interactswiththecullindomainofANAPC2andalsointeractswithUBE2D2. APC11showsbothacytoplasmicandnuclearlocalization. APC11isexpressedathighlevelsinskeletalmuscleandheart;inmoderatelevelsinbrain,kidney,andliver;andatlowlevelsincolon,thymus,spleen,smallintestine,placenta,lungandperipheralbloodleukocyte. APC11isamemberoftheRING-typezincfingerfamilyandisauto-ubiquitinylated.

Synonyms

rabbitanti-Apc11Antibody,Anaphasepromotingcomplexsubunit11homologantibody,APC11anaphasepromotingcomplexsubunit11homologantibody,Cyclosomesubunit11antibody,HepatocellularcarcinomaassociatedRINGfingerproteinantibody,HSPC214antibody,Apc

Immunogen

Thisantibodywaspreparedfromwholerabbitserumproducedbyrepeatedimmunizationswithasyntheticpeptidecorrespondingtoaminoacids76-84ofHumanAPC11(C-terminal)coupledtoKLH.

ImmunogenType

Peptide

StorageCondition

Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.

ApplicationNote

ThisantibodyreactswithhumanAPC11bywesternblotandimmunoprecipitation. Theantibodyimmunoprecipitatesinvitrotranslatedproteinandproteinfromoverexpressingcelllysates(usingHeLaandNIH-3T3,andothers). Coimmunoprecipitationofrelatedproteins(APC2)doesoccur. A9.8kDabandcorrespondingtohumanAPC11isdetected.MostcelllinesortissuesexpressingAPC11canbeusedasapositivecontrol. Researchersshoulddetermineoptimaltitersforotherapplications.

Purity/Specifity

Thisproductismonospecificantiserumprocessedbydelipidationanddefibrinationfollowedbysterilefiltration.ThisproductreactswithhumanandmouseAPC11.CrossreactivitymayalsooccurwithAPC11fromothersources. SufficientsequencedifferencesexisttosuggestthatthisantibodywouldnotreactwithotherRINGboxproteinssuchasROC1andROC2.

DisclaimerNote-General

Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.

品牌介绍

ROCKLAND

Rockland Immunochemicals Inc. 成立于1962年，是一家全球性的生物技术公司，为功能基因组学，基因治疗和药物发现市场的基础，应用和临床研究制造领先的研究工具。

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