Rockland/AML1-ETO Antibody/100-401-V33/100 µL,Rockland,,Rockland,rockland-inc,Rockland Immunochemicals Inc,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Rockland/AML1-ETO Antibody/100-401-V33/100 µL

产品编号：100-401-V33

市场价：¥7180.00

场地：美国(厂家直采)

产品分类：抗体类>一抗>功能性抗体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$359.00

品牌： Rockland

公司：Rockland Immunochemicals Inc.

公司分类：

商品介绍

AML1-ETOAntibodyProperties

Description

Anti-AML1-ETO(RABBBIT)Antibody-100-401-V33

Host

Rabbit

TargetSpecies

Human

KnownCrossReactivity

Human

Clonality

PolyclonalIgG

Application

ELISA:1:500
ChIP:4µl/ChIP
WesternBlot:1:1,000

PhysicalState

Liquid(sterilefiltered)

ShippingCondition

DryIce

Format

Antiserum

Label

Unconjugated

Buffer

None

Preservative

0.05%(w/v)SodiumAzideand0.05%ProClin300

StABIlizer

None

GeneName

RUNX1

RelevantLinks

UniProtKB-Q01196
GeneID-861
NCBI-NP_001001890

AML1-ETOAntibodyDescription

Background

ThisantibodyspecificallyrecognizestheAML1(RUNX1)(UniProtKB/Swiss-ProtentryQ01196)-ETO(RUNX1T1)(UniProtKB/Swiss-ProtentryQ06455)fusionproteinthatarisesduetoatranslocationbetweenchromosome8and22.Thistranslocationisoneofthemostfrequentkaryotypicabnormalitiesobservedinacutemyeloidleukaemia.Itproducesachimericalgenemadeupofthe5’-regionofAML1andthe3’-regionofETO.Thechimericalproteinisthoughttoassociatewiththenuclearcorepressor/histonedeacetylasecomplextoblockhematopoieticdifferentiation.Anti-AML1-ETOAntibodyisidealforresearchinCancerandGeneExpression.

Synonyms

Runt-relatedtranscriptionfactor1,Acutemyeloidleukemia1protein,Core-bindingfactorsubunitalpha-2,CBF-alpha-2,OncogeneAML-1,Polyomavirusenhancer-bindingprotein2alphaBsubunit,PEA2-alphaB,PEBP2-alphaB,SL3-3enhancerfactor1alphaBsubunit,SL3/AKVcore-bindingfactoralphaBsubunit

Immunogen

Anti-AML1-ETOAntibodywasproducedinrabbitsbyrepeatedimmunizationswithasyntheticpeptideofhumanAML1-ETO.

ImmunogenType

Peptide

StorageCondition

Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.

ApplicationNote

Anti-AML1-ETOAntibodyissuitableforChromatinImmunoprecipitation,ELISAandWesternBlots.Specificconditionsforreactivityshouldbeoptimizedbytheenduser. Expectabandapproximately80kDaintheappropriatecelllysateorextract.

Purity/Specifity

Anti-AML1-ETOAntibodyismonospecificantiserumprocessedbydelipidationanddefibrinationfollowedbysterilefiltration.ThisproductreactswithhumanAML1-ETO. CrossreactivitywithAML1-ETOfromothersourcesisnotknown.

DisclaimerNote-General

Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.

品牌介绍

ROCKLAND

Rockland Immunochemicals Inc. 成立于1962年，是一家全球性的生物技术公司，为功能基因组学，基因治疗和药物发现市场的基础，应用和临床研究制造领先的研究工具。

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