Rockland/ADAP Antibody/600-401-X70/100 µg,Rockland,,Rockland,rockland-inc,Rockland Immunochemicals Inc,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Rockland/ADAP Antibody/600-401-X70/100 µg

产品编号：600-401-X70

市场价：¥7180.00

场地：美国(厂家直采)

产品分类：抗体类>一抗>功能性抗体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$359.00

品牌： Rockland

公司：Rockland Immunochemicals Inc.

公司分类：

商品介绍

ADAPAntibodyProperties

Description

Anti-ADAP(RABBIT)Antibody-600-401-X70

Host

Rabbit

TargetSpecies

Human

KnownCrossReactivity

Human,mouse

Clonality

Polyclonal

Application

ELISA:1:5000-1:10000
IFMicroscopy:20µg/mL
WesternBlot:0.5-1µg/mL
OtherDilution:Immunocytochemistry:10µg/mL

PhysicalState

Liquid(sterilefiltered)

ShippingCondition

DryIce

Format

IgG

Label

Unconjugated

Concentration

1mg/mLbyUVabsorbanceat280nm

Buffer

0.01MSodiumPhosphate,0.25MSodiumChloride,pH7.2

Preservative

0.02%(w/v)SodiumAzide

StABIlizer

None

GeneName

FYB

RelevantLinks

UniProtKB-O15117
GeneID-2533
NCBI-NP_001456

ADAPAntibodyDescription

Background

Theadhesionanddegranulationadaptorprotein(ADAP)wasinitiallyidentifiedasamolecularadapterthatcouplesTcellreceptor(TCR)stimulationtotheAvidityofintegrinsgoverningTcelladhesion.TCRstimulationpromotestheformationofamulti-proteincomplexcontainingCARMA1,MALT1,andBCL-10,whichthroughtheassociationofADAP,ultimatelyactivatestheNF-kBfamilyoftranscriptionfactors.MorerecentexperimentshaveshownthatADAPcontrolsoptimalTcellproliferation,cytokineproduction,andexpressionoftheBcl-2familymemberBcl-x(L),suggestingthatADAPregulatesTcellactivationbypromotingantigen-dependentTcell-antigenpresentingcell(APC)activation.AtleastthreeisoformsofADAPareknowntoexist.

Synonyms

ADAPAntibody,ADAP,PRO0823,SLAP-130,SLAP130,FYN-bindingprotein,Adhesionanddegranulationpromotingadaptorprotein,ADAP

Immunogen

Anti-ADAPantibodywaspreparedfromwholerabbitserumproducedbyrepeatedimmunizationswitha20aminoacidsyntheticpeptidefromneartheC-terminusofhumanADAP.

ImmunogenType

Peptide

StorageCondition

Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.

ApplicationNote

Anti-ADAPAntibodyhasbeentestedforuseinELISA,Immunocytochemistry,ImmunofluorescenceandWesternBlotting.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectabandatapproximately119kDainWesternBlotsofspecificcelllysatesandtissues.

Purity/Specifity

Anti-ADAPAntibodywasaffinitypurifiedfrommonospecificantiserumbyimmunoaffinitychromatography.CrossreactivitywithADAPfromothersourceshasnotbeendetermined.

DisclaimerNote-General

Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.

品牌介绍

ROCKLAND

Rockland Immunochemicals Inc. 成立于1962年，是一家全球性的生物技术公司，为功能基因组学，基因治疗和药物发现市场的基础，应用和临床研究制造领先的研究工具。

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