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主营:antibodies ,dpolyclonal
℡ 4000-520-616
℡ 4000-520-616
Rockland/ADAP Antibody/600-401-X70/100 µg
产品编号:600-401-X70
市  场 价:¥7180.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$359.00
品      牌: Rockland
公      司:Rockland Immunochemicals Inc.
公司分类:
Rockland/ADAP Antibody/600-401-X70/100 µg
商品介绍

ADAPAntibodyProperties

Description
Anti-ADAP(RABBIT)Antibody-600-401-X70
Host
Rabbit
TargetSpecies
Human
KnownCrossReactivity
Human,mouse
Clonality
Polyclonal
Application
ELISA:1:5000-1:10000
IFMicroscopy:20µg/mL
WesternBlot:0.5-1µg/mL
OtherDilution:Immunocytochemistry:10µg/mL
PhysicalState
Liquid(sterilefiltered)
ShippingCondition
DryIce
Format
IgG
Label
Unconjugated
Concentration
1mg/mLbyUVabsorbanceat280nm
Buffer
0.01MSodiumPhosphate,0.25MSodiumChloride,pH7.2
Preservative
0.02%(w/v)SodiumAzide
StABIlizer
None
GeneName
FYB
RelevantLinks
UniProtKB-O15117
GeneID-2533
NCBI-NP_001456

ADAPAntibodyDescription

Background
Theadhesionanddegranulationadaptorprotein(ADAP)wasinitiallyidentifiedasamolecularadapterthatcouplesTcellreceptor(TCR)stimulationtotheAvidityofintegrinsgoverningTcelladhesion.TCRstimulationpromotestheformationofamulti-proteincomplexcontainingCARMA1,MALT1,andBCL-10,whichthroughtheassociationofADAP,ultimatelyactivatestheNF-kBfamilyoftranscriptionfactors.MorerecentexperimentshaveshownthatADAPcontrolsoptimalTcellproliferation,cytokineproduction,andexpressionoftheBcl-2familymemberBcl-x(L),suggestingthatADAPregulatesTcellactivationbypromotingantigen-dependentTcell-antigenpresentingcell(APC)activation.AtleastthreeisoformsofADAPareknowntoexist.
Synonyms
ADAPAntibody,ADAP,PRO0823,SLAP-130,SLAP130,FYN-bindingprotein,Adhesionanddegranulationpromotingadaptorprotein,ADAP
Immunogen
Anti-ADAPantibodywaspreparedfromwholerabbitserumproducedbyrepeatedimmunizationswitha20aminoacidsyntheticpeptidefromneartheC-terminusofhumanADAP.
ImmunogenType
Peptide
StorageCondition
Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.
ApplicationNote
Anti-ADAPAntibodyhasbeentestedforuseinELISA,Immunocytochemistry,ImmunofluorescenceandWesternBlotting.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectabandatapproximately119kDainWesternBlotsofspecificcelllysatesandtissues.
Purity/Specifity
Anti-ADAPAntibodywasaffinitypurifiedfrommonospecificantiserumbyimmunoaffinitychromatography.CrossreactivitywithADAPfromothersourceshasnotbeendetermined.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
品牌介绍

ROCKLAND


Rockland Immunochemicals Inc. 成立于1962年,是一家全球性的生物技术公司,为功能基因组学,基因治疗和药物发现市场的基础,应用和临床研究制造领先的研究工具。


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