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主营:antibodies ,dpolyclonal
℡ 4000-520-616
℡ 4000-520-616
Rockland/ADAM10 Antibody/200-401-949/100 µg
产品编号:200-401-949
市  场 价:¥7180.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$359.00
品      牌: Rockland
公      司:Rockland Immunochemicals Inc.
公司分类:
Rockland/ADAM10 Antibody/200-401-949/100 µg
商品介绍

ADAM10AntibodyProperties

Description
Anti-ADAM10(RABBIT)Antibody-200-401-949
Host
Rabbit
TargetSpecies
Human
KnownCrossReactivity
human
Clonality
Polyclonal
Application
ELISA:1:5,000-1:20,000
IFMicroscopy:1:250-1:1,000
WesternBlot:1:500to1:2000
Immunohistochemistry:1:100-1:800
OtherDilution:UserOptimized
PhysicalState
Liquid(sterilefiltered)
ShippingCondition
DryIce
Format
IgG
Label
Unconjugated
Concentration
1.0mg/mLbyUVabsorbanceat280nm
Buffer
0.02MPotassiumPhosphate,0.15MSodiumChloride,pH7.2
Preservative
0.01%(w/v)SodiumAzide
StABIlizer
None
GeneName
ADAM10
RelevantLinks
NCBI-4557251
UniProtKB-O14672
GeneID-102

ADAM10AntibodyDescription

Background
Proinflammatorycytokinetumornecrosisfactor-a(TNF-a)contributestoavarietyofinflammatoryresponsesandprogrammedcelldeath.Notchreceptoranditsligandparticipateincellfatedecisionsduringvertebratedevelopmentandareassociatedwithseveralhumandisorders,includingaT-celllymphoma.TNF-a,notch,anditsliganddelta,areallmembrane-boundmolecules,whicharecleavedbyproteasestoreleasematureproteinsorfunctionalreceptor. ADAM10,ametalloprotease-disintegrininthefamilyofmammalianADAM(foradisintegrinandmetalloprotease),wasrecentlyidentifiedtocleaveTNF-a,notchanditsliganddelta. Thegenesencodinghuman,mouse,andbovineADAM10wererecentlyclonedanddesignatedADAM10,kuzbanian(KUZ)andMADM,respectively. ADAM10mRNAisexpressedinavarietyofhumanandbovinetissues.Anti-ADAM10isidealforinvestigatorsinvolvedinNF-kappaB,Apoptosis,CytokinsandGrowthfactorresearch.
Synonyms
Adisintegrinandmetalloproteasedomain10antibody,ADisintegrinAndMetalloproteinaseDomain10antibody,ADAM10antibody,ADAMmetallopeptidasedomain10antibody,CD156cantibod,KUZ,MADM
Immunogen
ThisIgGfractionantibodywaspreparedfromwholerabbitserumproducedbyrepeatedimmunizationswithasyntheticpeptidecorrespondingtoaregionnearthecarboxyterminusofhumanADAM10protein.
ImmunogenType
Peptide
StorageCondition
Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.
ApplicationNote
ADAM10antibodyhasbeentestedforuseinELISA,immunohistochemistryandwesternblotting. Specificconditionsforreactivityshouldbeoptimizedbytheenduser. Expectabandapproximately84kDainsizecorrespondingtoADAM10proteinbywesternblottingintheappropriatecelllysateorextract.
Purity/Specifity
ADAM10IgGfractionantibodyisdirectedagainsthumanADAM10protein. TheproductwaspurifiedfrommonospecificantiserumbyDEAEchromatography. ABLASTanalysiswasusedtosuggestcross-reactivitywithADAM10proteinfromhuman,bovineandratbasedon100%homologywiththeimmunizingsequence. PartialreactivityisexpectedagainstADAM10frommousebasedonasingleaminoacidchangerelativetothissequence. Reactivityagainsthomologuesfromothersourcesisnotknown.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
品牌介绍

ROCKLAND


Rockland Immunochemicals Inc. 成立于1962年,是一家全球性的生物技术公司,为功能基因组学,基因治疗和药物发现市场的基础,应用和临床研究制造领先的研究工具。


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