Rockland/5-Lipoxygenase phospho S523 Antibody/600-401-D03/100 µL,Rockland,,Rockland,rockland-inc,Rockland Immunochemicals Inc,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Rockland/5-Lipoxygenase phospho S523 Antibody/600-401-D03/100 µL

产品编号：600-401-D03

市场价：¥7100.00

场地：美国(厂家直采)

产品分类：抗体类>一抗>功能性抗体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$355.00

品牌： Rockland

公司：Rockland Immunochemicals Inc.

公司分类：

商品介绍

5-LipoxygenasephosphoS523AntibodyProperties

Description

Anti-5-LipoxygenasepS523(Rabbit)Antibody-600-401-D03

Host

Rabbit

TargetSpecies

Human

KnownCrossReactivity

human,rat,mouse

Clonality

Polyclonal

Application

ELISA:1:10,000
WesternBlot:1:1000

PhysicalState

Liquid

ShippingCondition

DryIce

Format

IgG

Label

Unconjugated

Buffer

0.01MHEPES,0.15MSodiumChloride,pH7.5

StABIlizer

0.1mg/mlBovineSerumAlbumin(BSA)-IgGandProteasefree,50%(v/v)Glycerol

GeneName

ALOX5

RelevantLinks

UniProtKB-P09917
GeneID-240
UniProtKB-P09917.2

5-LipoxygenasephosphoS523AntibodyDescription

Background

5-LipoxygenasepS523antibodyrecognizestheenzyme5-lipoxygenase(5-LO)whichplaysakeyroleinregulatingtheproductionofleukotrienes(LTs).OverproductionofLTscontributestoseveraldiseases,mostnotablychronicinflammatorydiseases,includingasthma,fibrosisandatherosclerosis.Recentworkhasdemonstratedthattheactivityof5-LOisregulatedbyPKAphosphorylationofserine-523in5-LO.Undernormalconditions,thisphosphorylationmaybeimportantinlimitinginflammation.AbnormalsignalingthroughcAMPandPKA,then,couldcontributetoavarietyofdiseases,includingthosecharacterizedbychronicinflammation.Thephospho-specificantibodytoSer523on5-LOisthuslikelytoprovideavaluabletoolforstudiesoftheroleof5-LOregulationindiseasessuchasasthma,fibrosisandatherosclerosis.Anti-5-LipoxygenasepS523antibodyisidealforinvestigatorsinvolvedinCellSignaling,Neuroscience,SignalTransductionresearch.

Synonyms

Arachidonate5-lipoxygenase,5-LO

Immunogen

Anti-5-LipoxygenasepS523Antibodywasproducedbyrepeatedimmunizationswithsyntheticphospho-peptidecorrespondingtoaminoacidresiduessurroundingSer523.

ImmunogenType

Peptide

PostTranslationalModification

Phosphorylation

StorageCondition

Storevialat-20°Cpriortoopening. Thisproductisstableat4°Casanundilutedliquid. Forextendedstorage,aliquotcontentsandfreezeat-20°Corbelow. Avoidcyclesoffreezingandthawing.Diluteonlypriortoimmediateuse.

ApplicationNote

Anti-5-LipoxygenasepS523antibodyissuitableforuseinWesternBlottingandELISA.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectabandofapproximately80kDacorrespondingtothe80kDa5-LOproteinsphosphorylatedatSer523.

Purity/Specifity

Anti-5-LipoxygenasepS523Antibodyisdirectedagainsthuman5-LipoxygenasephosphorylatedatS523.Theantibodyisaffinitypurifiedfrommonospecificantiserumbyimmunoaffinitypurification.Reactivityisexpectedfromthefollowingspeciesbasedon100%sequencehomology:nonhumanprimates.Crossreactivitywith5-LipoxygenasepS523fromotherspecieshasnotbeendetermined.

DisclaimerNote-General

Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.

品牌介绍

ROCKLAND

Rockland Immunochemicals Inc. 成立于1962年，是一家全球性的生物技术公司，为功能基因组学，基因治疗和药物发现市场的基础，应用和临床研究制造领先的研究工具。

产品列表：

No.	品牌	货号	名称	规格
1	ROCKLAND	100-4191	Superoxide Dismutase Antibody	2mL
2	ROCKLAND	100-4140	Acid Phosphatase Antibody	2ml
3	ROCKLAND	200-301-U98	5-mC Antibody	50ug
4	ROCKLAND	200-301-065s	NF-kB p65 Antibody	25ul
5	ROCKLAND	200-301-065	NF-kB p65 Antibody	100ug
6	ROCKLAND	200-303-400	ATM phospho S1981 Peroxidase Conjugated Antibody	100ug
7	ROCKLAND	600-401-952	IRAK-2 Antibody	100ug
8	ROCKLAND	609-1606	Human IgA (alpha chain) Antibody Biotin Conjugated	1mg
9	ROCKLAND	600-401-147	Alpha-1-Trypsin Antibody	1mg
10	ROCKLAND	610-4610	Mouse κ (kappa chain) Antibody Biotin Conjugated	1mg
11	ROCKLAND	609-1316	Human IgG (H&L) Antibody Peroxidase Conjugated Pre-Adsorbed	2mg
12	ROCKLAND	613-4528	Sheep IgG (H&L) Secondary Antibody Alkaline Phosphatase Conjugated Pre-Adsorbed	500ug
13	ROCKLAND	805-7602	Fab Goat IgG Antibody Biotin Conjugated	1mg
14	ROCKLAND	714-406-002	F(ab')2 Swine IgG (H&L) Antibody Biotin Conjugated	500ug
15	ROCKLAND	600-401-147S	Alpha-1-Trypsin Antibody	25ul