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主营:antibodies ,dpolyclonal
℡ 4000-520-616
℡ 4000-520-616
Rockland/ARHGAP22 phospho S397 Antibody/600-401-J12/50 µg
产品编号:600-401-J12
市  场 价:¥7180.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$359.00
品      牌: Rockland
公      司:Rockland Immunochemicals Inc.
公司分类:
Rockland/ARHGAP22 phospho S397 Antibody/600-401-J12/50 µg
商品介绍

ARHGAP22phosphoS397AntibodyProperties

Description
Anti-ARHGAP22pS397(RABBIT)Antibody-600-401-J12
Host
Rabbit
TargetSpecies
Mouse
KnownCrossReactivity
Human,Mouse,Rat
Clonality
Polyclonal
Application
ELISA:1:20,000-1:60,000
IFMicroscopy:1:100-1:500
WesternBlot:1µg/ml
Immunohistochemistry:1:100-1:500
OtherDilution:UserOptimized
PhysicalState
Liquid(sterilefiltered)
ShippingCondition
DryIce
Format
IgG
Label
Unconjugated
Concentration
1.07mg/mlbyUVabsorbanceat280nm
Buffer
0.02MPotassiumPhosphate,0.15MSodiumChloride,pH7.2
Preservative
None
StABIlizer
50%(v/v)Glycerolwith1mg/mlBovineSerumAlbumin(BSA)
GeneName
ARHGAP22
RelevantLinks
UniProtKB-Q8BL80
NCBI-NP_722495
GeneID-239027

ARHGAP22phosphoS397AntibodyDescription

Background
ARHGAP22isaRhoGTPase-activatingproteininvolvedinthesignaltransductionpathwaythatregulatesendothelialcellcapillarytubeformationduringangiogenesis.ItactsasaGTPaseactivatorforRAC1byconvertingittoaninactiveGDP-boundstateandalsoinhibitsRAC1-dependentlamellipodiaformation.ItmayalsoplayaroleintranscriptionregulationviaitsinteractionwithVEZF1,byregulatingactivityoftheendothelin-1(EDN1)promoter.Anti-ARHGAP22[pSer397]antibodyisidealforresearchersinterestedinDiabetesResearch,LipidandMetabolismresearch.
Synonyms
rabbitanti-ARHGAPpS397antibody,ARHGAP22,ARHGAP-22,Rho-typeGTPase-activatingprotein22,RHOGAP2,RhoGTPaseactivatingprotein22,rhoGTPase-activatingprotein22
Immunogen
ARHGAP22affinitypurifiedantibodywaspreparedfromwholerabbitserumproducedbyrepeatedimmunizationswithasyntheticphospho-peptidecorrespondingtotheregionsurroundingmousepS397regionofARHGAP22.
ImmunogenType
Peptide
PostTranslationalModification
Phosphorylation
StorageCondition
Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.
ApplicationNote
Anti-ARHGAP22pS397antibodyisusefulforELISA,WesternBlotandImmunostaining.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectabandapproximately~77.8kDacorrespondingtotheappropriatecelllysateorextract.
Purity/Specifity
Anti-ARHGAP22pS397wasaffinitypurifiedfrommonospecificantiserumbyimmunoaffinitychromatography.ThisantibodyisspecificforphosphorylatedARHGAP22atSerine397.ItalsorecognizestheS22->AmutationbutnottheS397->Amutation.ABLASTanalysiswasusedtosuggestcross-reactivitywithMouse,RatandHumanbasedon100%sequencehomology.Cross-reactivitywithARHGAP22pS397fromothersourceshasnotbeendetermined.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
品牌介绍

ROCKLAND


Rockland Immunochemicals Inc. 成立于1962年,是一家全球性的生物技术公司,为功能基因组学,基因治疗和药物发现市场的基础,应用和临床研究制造领先的研究工具。


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