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主营:antibodies ,dpolyclonal
℡ 4000-520-616
℡ 4000-520-616
Rockland/APC6 phospho T580 Antibody/600-401-876/100 µg
产品编号:600-401-876
市  场 价:¥7180.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$359.00
品      牌: Rockland
公      司:Rockland Immunochemicals Inc.
公司分类:
Rockland/APC6 phospho T580 Antibody/600-401-876/100 µg
商品介绍

APC6phosphoT580AntibodyProperties

Description
Anti-APC6pT580(RABBIT)Antibody-600-401-876
Host
Rabbit
TargetSpecies
Human
KnownCrossReactivity
human
Clonality
Polyclonal
Application
ELISA:1:1,000-1:10,000
IFMicroscopy:UserOptimized
WesternBlot:1:500-1:3,000
OtherDilution:UserOptimized
PhysicalState
Liquid(sterilefiltered)
ShippingCondition
DryIce
Format
IgG
Label
Unconjugated
Concentration
0.97mg/mLbyUVabsorbanceat280nm
Buffer
0.02MPotassiumPhosphate,0.15MSodiumChloride,pH7.2
Preservative
0.01%(w/v)SodiumAzide
StABIlizer
None
GeneName
CDC16
RelevantLinks
NCBI-37537763
UniProtKB-Q13042
GeneID-8881

APC6phosphoT580AntibodyDescription

Background
APC6(alsoknownasCelldivisioncycleprotein16homolog(CDC16Hs),anaphasepromotingcomplexsubunit6,andcyclosomesubunit6)isacomponentoftheanaphasepromotingcomplex/cyclosome(APC/C),acellcycle-regulatedubiquitinligasethatcontrolsprogressionthroughmitosisandtheG1phaseofthecellcycle.  TheAPC/Ciscomposedofatleast11subunits.  APC6interactswithPPP5CandCDC20.ThisproteincolocalizeswithCDC27tothecentrosomeatallstagesofthecellcycleandtothemitoticspindle. Splicevariantshavebeendescribedforthisprotein.
Synonyms
rabbitanti-APC6pT580Antibody,APC6,APC-6,Anaphasepromotingcomplexsubunit6antibody,CDC16Hsantibody,Celldivisioncycle16homologantibody,Celldivisioncycleprotein16homologantibody,Cyclosomesubunit6antibody
Immunogen
Thisaffinitypurifiedantibodywaspreparedfromwholerabbitserumproducedbyrepeatedimmunizationswithasyntheticpeptidecorrespondingtoaminoacids575-588ofHumanApc6protein.
ImmunogenType
Peptide
PostTranslationalModification
Phosphorylation
StorageCondition
Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.
ApplicationNote
ThisaffinitypurifiedantibodyhasbeentestedforuseinELISAandwesternblot.  Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectaband~72kDa,71.5kDaor65.9kDainsizecorrespondingtoisoformsofAPC6bywesternblottingintheappropriatecelllysateorextract.
Purity/Specifity
Thisproductisanaffinitypurifiedantibodyproducedbyimmunoaffinitychromatographyusingphosphopeptidecoupledtoagarosebeadsfollowedbysolidphaseadsorption(s)againstnon-phosphopeptideandnon-specificpeptidetoremoveanyunwantedreactivities.ThisantibodyisspecificforphosphorylatedhumanAPC6proteinatthepT580residue.BLASTanalysisindicates100%homologyoftheimmunizingsequencewithAPC6fromhuman. Nocrossreactivityisexpectedagainsthomologuesfromothersources. Thisantibodyisexpectedtoreactwithallisoformsofthisprotein. Minimalreactivityisexpectedwiththenon-phosphorylatedformoftheprotein.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
品牌介绍

ROCKLAND


Rockland Immunochemicals Inc. 成立于1962年,是一家全球性的生物技术公司,为功能基因组学,基因治疗和药物发现市场的基础,应用和临床研究制造领先的研究工具。


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