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主营:antibodies ,dpolyclonal
℡ 4000-520-616
℡ 4000-520-616
Rockland/APC4 Antibody/600-401-Y34/100 µg
产品编号:600-401-Y34
市  场 价:¥7180.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$359.00
品      牌: Rockland
公      司:Rockland Immunochemicals Inc.
公司分类:
Rockland/APC4 Antibody/600-401-Y34/100 µg
商品介绍

APC4AntibodyProperties

Description
Anti-APC4(RABBIT)Antibody-600-401-Y34
Host
Rabbit
TargetSpecies
Human
KnownCrossReactivity
Human,mouse,rat
Clonality
Polyclonal
Application
ELISA:1:10,000-1:20,000
WesternBlot:1-2µg/mL
Immunohistochemistry:5µg/mL
PhysicalState
Liquid(sterilefiltered)
ShippingCondition
DryIce
Format
IgG
Label
Unconjugated
Concentration
1mg/mLbyUVabsorbanceat280nm
Buffer
0.01MSodiumPhosphate,0.25MSodiumChloride,pH7.2
Preservative
0.02%(w/v)SodiumAzide
StABIlizer
None
GeneName
ANAPC4
RelevantLinks
UniProtKB-Q9UJX5
GeneID-29945
NCBI-Q9UJX5

APC4AntibodyDescription

Background
Cellcycleregulatedproteinubiquitinationanddegradationwithinsubcellulardomainsisthoughttobeessentialforthenormalprogressionofmitosis.APC4isahighlyconservedcomponentoftheanaphasepromotingcomplex/cyclosome(APC/C),acellcycle-regulatedE3ubiquitinligasethatcontrolsprogressionthroughmitosisandtheG1phaseofthecellcycle.APC/CisresponsIBLefordegrADInganaphaseinhibitors,mitoticcyclins,andspindle-associatedproteinsensuringthateventsofmitosistakeplaceinpropersequence.TheindividualAPC/CcomponentsmRNAandproteinlevelsareexpressedatapproximatelythesamelevelsinmosttissuesandcelllines,suggestingthattheyperformtheirfunctionsaspartofacomplex.WhilelittleisknownofAPC4,itisthoughtthatAPC4associateswithotherAPC/CcomponentsAPC1,APC5,andCDC23interdependently,suchthatlossofanyonesubunitreducesbindingbetweentheremainingthree.
Synonyms
APC4Antibody,APC4,APC4,Anaphase-promotingcomplexsubunit4,Cyclosomesubunit4
Immunogen
Anti-APC4antibodywaspreparedfromwholerabbitserumproducedbyrepeatedimmunizationswitha14aminoacidsyntheticpeptideneartheN-terminusofhumanAPC4.
ImmunogenType
Peptide
StorageCondition
Storevialat-20°Cpriortoopening.Aliquotcontentsandfreezeat-20°Corbelowforextendedstorage.Avoidcyclesoffreezingandthawing.Centrifugeproductifnotcompletelyclearafterstandingatroomtemperature.Thisproductisstableforseveralweeksat4°Casanundilutedliquid.Diluteonlypriortoimmediateuse.
ApplicationNote
Anti-APC4AntibodyhasbeentestedforuseinELISA,WesternBlotting,andImmunohistochemistry.Specificconditionsforreactivityshouldbeoptimizedbytheenduser.Expectabandatapproximately92kDainWesternBlotsofspecificcelllysatesandtissues.
Purity/Specifity
Anti-APC4Antibodywasaffinitypurifiedfrommonospecificantiserumbyimmunoaffinitychromatography.CrossreactivitywithAPC4fromothersourceshasnotbeendetermined.
DisclaimerNote-General
Thisproductisforresearchuseonlyandisnotintendedfortherapeuticordiagnosticapplications.Pleasecontactatechnicalservicerepresentativeformoreinformation.AllproductsofanimaloriginmanufacturedbyRocklandImmunochemicalsarederivedfromstartingmaterialsofNorthAmericanorigin.CollectionwasperformedinUnitedStatesDepartmentofAgriculture(USDA)inspectedfacilitiesandallmaterialshavebeeninspectedandcertifiedtobefreeofdiseaseandsuitableforexportation.Allpropertieslistedaretypicalcharacteristicsandarenotspecifications.Allsuggestionsanddataareofferedingoodfaithbutwithoutguaranteeasconditionsandmethodsofuseofourproductsarebeyondourcontrol.Allclaimsmustbemadewithin30daysfollowingthedateofdelivery.TheProspectiveusermustdeterminethesuitabilityofourmaterialsbeforeadoptingthemonacommercialscale.SuggestedusesofourproductsarenotrecommendationstouseourproductsinviolationofanypatentorasalicenseunderanypatentofRocklandImmunochemicals,Inc.Ifyourequireacommerciallicensetousethismaterialanddonothaveone,thenreturnthismaterial,unopenedto:RocklandInc.,P.O.BOX5199,Limerick,Pennsylvania,USA.
品牌介绍

ROCKLAND


Rockland Immunochemicals Inc. 成立于1962年,是一家全球性的生物技术公司,为功能基因组学,基因治疗和药物发现市场的基础,应用和临床研究制造领先的研究工具。


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